Members of the Organic Anion Transporter (OAT) Family (organic-anion-transporting polypeptides, OATP) are membrane transport proteins or 'transporters' that mediate the …

Dec 9, 2024 · Opioid Addiction Treatment Program (OATP) – Located at John Cochran. Provides specialized treatment services for opioid addiction. Substance Abuse Rehabilitation and …

Here, we developed in vitro and in silico models for identification and prediction of specific and general inhibitors of OATP1B1, OATP1B3, and OATP2B1. The maximal transport activity …

Organic anion transporting polypeptides (OATPs) are membrane proteins that mediate the uptake of a wide range of substrates across the plasma membrane of various cells and tissues. They …

Organic anion-transporting polypeptides (OATPs) are membrane transporters that facilitate the movements of certain compounds, such as drugs, into a cell. Their activity level can influence …

Kullak-Ublick GA, Ismair MG, Stieger B, Landmann L, Huber R, Pizzagalli F, et al. Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of …

Dec 9, 2024 · An overview of the regulation of OATP expression and clinically important single-nucleotide polymorphisms (SNPs) will be summarized, and challenges of physiologically …

The organic anion transporting polypeptides (OATPs) are a superfamily of drug transporters involved in the uptake and disposition of a wide array of structurally divergent endogenous and …

Organic anion transporting polypeptides or OATPs are central transporters in the disposition of drugs and other xenobiotics. In addition, they mediate transport of a wide variety of …

Eleven members of the human organic anion transporter (OATP) family (grouped into six families) facilitate the Na(+)- independent transmembrane transport of various endo- and xenobiotics …