An intensive therapy for children with neuromotor disorders developed by Virginia Tech researchers shows promise for kids ...

Discover how next-generation kinase inhibitors are transforming clinical therapy byovercoming resistance and enhancing ...

Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of ...

Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its ...

In the February 10 Nature Medicine, scientists led by Jorge Llibre-Guerra and Randall Bateman at Washington University, St.

Young and colleagues suspected that many disease-associated mutations might contribute to disease by changing protein localization. For example, a mutation could make a protein unable to join a ...

However, such genomic discoveries in oncology have not translated into advances for non-cancerous disease since point mutations in a single cell would be unlikely to cause non-malignant disease. An ...

1Division of Cancer Genome Research, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), and National Center for Tumor Diseases (NCT), Heidelberg, Germany 2German Center for Lung ...

Proportion of mtDNA point mutations arising de novo in patients with mtDNA disease ... would actually represent recurrence despite absence of the mutation in the mother, 8 examples in 154 cases (17 ...

U.S. President Donald Trump's top economic adviser pointed to Alberta's capital as an example of a drug crisis that the U.S. government says is the impetus for sweeping tariffs on Canada.

dilution for IHC); criteria or cut-point used to define TP53 mutation status for the survival analysis; study prevalence of TP53 ‘mutation’ and ‘non-mutation’ subgroups; median survival of all ...