Cells have a natural editing system that allows them to rearrange genetic instructions to create different proteins from the ...

What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms. Next, the snRNPs U2 and U4/U6 appear to ...

Alternative RNA splicing is like a movie editor cutting and rearranging scenes from the same footage to create different versions of a film.

RNA splicing is a cellular process that is critical ... are cut out and the coding portions are spliced back together. This process is controlled by a large protein-RNA complex called the spliceosome.

RBP splicing factors are sequence-specific, binding to their cognate sequence motifs like a lock and key. “Because the binding pocket of the RBP matches the sequence motif, the RBP binds to the ...

RNA splicing is a cellular process that is critical ... are cut out and the coding portions are spliced back together. This process is controlled by a large protein-RNA complex called the spliceosome.

Working at the interface of RNA splicing and breast cancer biology, our current focus is on regulation of breast cancer metastasis driven by alternative splicing. We use molecular biology, genomics, ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical ...

The realization that most human genes generate multiple mRNAs encoding divergent protein isoforms via alternative splicing and polyadenylation has revealed extensive regulation that remains to be ...

Other ribozymes include self-splicing introns and the RNA component of the enzyme telomerase. Non-coding RNA molecules, such as miRNAs (miRNAs) and long non-coding RNAs (lncRNAs), play essential roles ...