Discovered that microtubules are critical for the movement and positioning of nuclei in the multinucleated skeletal muscle cell. Developed Drosophila models of muscle wasting in cancer cachexia and ...

Patients with degenerative diseases that attack skeletal muscle tissues, such as Duchenne muscular dystrophy, may soon benefit from novel stem cell therapies. A study has demonstrated how new ...

This work describes how skeletal muscle cell populations, including both the individual nuclei in multinucleated fibers and ...

Michael Duchen, an expert in mitochondrial biology at University College London, has studied the cell’s tiny powerhouses ... converted into striated, multinucleated skeletal myocytes, which ...

Whereas muscle fibers showed numerous signs of incomplete maturation in both the Ad-MSC- and BM-MSC-transplanted groups, iMSC-transplanted Col6a1 KO mice possessed the most multinucleated ...

This mRNA carries the instruction code that tells our cells how to do everything they ... to make the protein necessary for ...

B) Panel show two larval multinucleated muscles ... We currently are generating human skeletal muscle from human pluripotent stem cells. We will use this model to confirm and extend the paradigms that ...