Mitochondrial dysfunction characterizes a range of neurodegenerative ... In such conditions, abnormal mitochondrial dynamics and impaired mitochondrial biogenesis may lead to increased production ...

New research shows benzodiazepines impair mitochondrial function throughout the body, affecting hormone synthesis, energy ...

Shapeshifting mitochondria continually fuse and divide, but precisely how those dynamics ... mitochondrial network could be associated with more aggressive presentations of the disease," Dr ...

Mitochondrial homeostasis is crucial for the maintenance of cellular equilibrium. In neurons, which are non-regenerative cells, mitochondrial dysfunction ...

Disorders that impair mitochondrial function often involve early-onset skeletal problems, such as stunted growth and premature cartilage degeneration. Despite this link, the molecular mechanisms ...

A CRISPR/Cas9-based galactose screening identifies key mitochondrial genes involved in OXPHOS and oxidative metabolism, ...

Rachael’s research is in the area of mitochondrial rare diseases and what they can teach us about mitochondrial dynamics and regulation. Her interest in Rare Disease research has also led her to ...

Autism spectrum disorders (ASD) are neurodevelopmental ... We now show that NT induces release of extracellular mitochondrial DNA (mtDNA) that could act as "autoimmune" trigger.

The discovery could help scientists design new therapeutic agents to combat calcium overload of mitochondria in conditions such as heart failure and Alzheimer's disease. Mitochondrial calcium ...

"Although MFN2 is a leading causative gene in Charcot-Marie-Tooth, most other genes linked to the disease do not ... of its primary function in mitochondrial dynamics," explained Mariana Joaquim ...