Dendritic cells (DCs) actively participate in maintaining this balance. Under steady-state conditions, DCs remain in an immature state and do not mount an immune response against circulating self ...

However, two papers by Stern and colleagues 1,2 now indicate that mouse immature dendritic cells are also able to bypass the antigen-internalization stage by processing antigens extracellularly ...

Without NF-κB p65, dendritic cells get stuck in an immature state and cannot promote T cells to fight the infection. In ...

We here evaluated the effects of LBH589 on human myeloid dendritic cells (DCs) at clinically relevant concentrations. Exposure to LBH589 affected the surface molecule expression on immature and ...

Without NF-κB p65, dendritic cells get stuck in an immature state and cannot promote T cells to fight the infection. In contrast, dengue virus really stimulates dendritic cells to make lots of ...