Figure 1: Model of Spir and Cappuccino cooperation in actin nucleation/polymerization. Together these findings establish actin nucleation by multiple WH2 domains as a general mechansim.

These are members of a team from Rice University and Baylor College of Medicine that deciphered the 3-D structure of actin nucleation, a critical but fleeting process that takes place thousands of ...

But in 2008, Mukherjee stumbled across a new and much faster way to cause intracellular mayhem. Studying bacterial interactions with actin is still throwing up new mysteries. These microbes all enjoy ...

It exists primarily as monomers (G-actin) bound by G-actin binding proteins that prevent spontaneous nucleation of new actin filaments, making nucleation the rate-limiting step in forming filamentous ...

The forces induced by actin polymerization drive the movement of the plasma membrane and are essential for cellular functions ...